E-4031 dihydrochloride from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemE-4031 dihydrochloride
CompanyTocris Bioscience, a Bio-Techne Brand
Price Pricing Info Supplier Page View Supplier Product Page
Catalog Number1808/10
Quantity10 mg (also 50 mg)
Brand/TrademarkTocris, a Bio-Techne Brand
Purity0.98
Molecular Weight474.44
Molecule NameN-[4-[[1-[2-(6-Methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]methanesulfonamide dihydrochloride
FormulaC₂₁H₂₇N₃O₃S.2HCl
StorageDesiccate at RT

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

(1) Sigma non-opioid receptor 1 is a potential therapeutic target for long QT syndromeNat Cardiovasc ResFebruary 1, 2022Song L, Bekdash R, Morikawa K, Quejada JR, Klein AD, Aina-Badejo D, Yoshida K, Yamamoto HE, Chalan A, Yang R, et al.

(2) Electrophysiological measurement of ion channels on plasma/organelle membranes using an on-chip lipid bilayer systemScientific reportsNovember 30, 2018Kamiya K, Osaki T, Nakao K, Kawano R, Fujii S, Misawa N, Hayakawa M, Takeuchi S.

(3) Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K⁺ channelNature communicationsOctober 19, 2018Veldkamp MW, Geuzebroek GSC, Baartscheer A, Verkerk AO, Schumacher CA, Suarez GG, Berger WR, Casini S, van Amersfoorth SCM, Scholman KT, et al.

(6) An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived CardiomyocytesFrontiers in physiologyJanuary 1, 2017McKeithan WL, Savchenko A, Yu MS, Cerignoli F, Bruyneel AAN, Price JH, Colas AR, Miller EW, Cashman JR, Mercola M.

(11) Characterization of hERG1 channel role in mouse colorectal carcinogenesisCancer medicineOctober 1, 2013Fiore A, Carraresi L, Morabito A, Polvani S, Fortunato A, Lastraioli E, Femia AP, De Lorenzo E, Caderni G, Arcangeli A.

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6/11/2019E-4031 Shortens Cardiac Action Potential Duration Chintan KoyaniE-4031 significantly shortened action potential duration of guinea pig ventricular cardiomyocytes.

E-4031 dihydrochloride